AHCODA-DB

Experiment name: Complex Genetics of Behavior. BXDs in the Automated Home-Cage (Loos et al 2017)
LSID: http://syli.cz/urn:lsid:public.sylics.com:experiment:E257-9325-GA46

TreatmentAmountAdministration routeAdministration time


Treatment info:
Complex Genetics of Behavior: BXDs in the Automated Home-Cage.

Loos M, Verhage M, Spijker S, Smit AB

act
This chapter describes a use case for the genetic dissection and automated analysis of complex behavioral traits using the genetically diverse panel of BXD mouse recombinant inbred strains. Strains of the BXD resource differ widely in terms of gene and protein expression in the brain, as well as in their behavioral repertoire. A large mouse resource opens the possibility for gene finding studies underlying distinct behavioral phenotypes, however, such a resource poses a challenge in behavioral phenotyping. To address the specifics of large-scale screening we describe how to investigate: (1) how to assess mouse behavior systematically in addressing a large genetic cohort, (2) how to dissect automation-derived longitudinal mouse behavior into quantitative parameters, and (3) how to map these quantitative traits to the genome, deriving loci underlying aspects of behavior.

KEYWORDS:
Automated home-cage; Genetic effect size; High-throughput; Inbred mouse strains; Mouse phenomics; PhenoTyper; Reference database; Sheltering; Spontaneous behavior; Systematic behavioral profile

Mouse info:
Mouse ID Strain Coat color Genotype Ear tag Internal ID Sex Date of Birth Sub experiment 1 Sub experiment 2 Sub experiment 3
PH00033 BXD40 unknown male 00-00-0000
PH00034 BXD40 unknown male 00-00-0000
PH00035 BXD40 unknown male 00-00-0000
PH00036 BXD42 unknown male 00-00-0000
PH00064 BXD40 unknown male 00-00-0000
PH00065 BXD40 unknown male 00-00-0000
PH00130 BXD33 unknown male 00-00-0000
PH00136 BXD11 unknown male 00-00-0000
PH00137 BXD34 unknown male 00-00-0000
PH00141 B6D2F1/J unknown male 00-00-0000
PH00142 BXD32 unknown male 00-00-0000
PH00143 BXD32 unknown male 00-00-0000
PH00150 BXD06 unknown male 00-00-0000
PH00151 BXD34 unknown male 00-00-0000
PH00153 BXD34 unknown male 00-00-0000
PH00155 BXD34 unknown male 00-00-0000
PH00170 BXD42 unknown male 00-00-0000
PH00185 BXD87 unknown male 00-00-0000
PH00241 BXD33 unknown male 00-00-0000
PH00242 BXD33 unknown male 00-00-0000
PH00243 BXD33 unknown male 00-00-0000
PH00244 BXD31 unknown male 00-00-0000
PH00245 BXD31 unknown male 00-00-0000
PH00250 BXD11 unknown male 00-00-0000
PH00253 BXD02 unknown male 00-00-0000
PH00254 BXD02 unknown male 00-00-0000
PH00255 BXD06 unknown male 00-00-0000
PH00256 BXD06 unknown male 00-00-0000
PH00264 BXD11 unknown male 00-00-0000
PH00267 BXD33 unknown male 00-00-0000
PH00268 BXD33 unknown male 00-00-0000
PH00269 BXD33 unknown male 00-00-0000
PH00277 B6D2F1/J unknown male 00-00-0000
PH00278 B6D2F1/J unknown male 00-00-0000
PH00280 B6D2F1/J unknown male 00-00-0000
PH00281 B6D2F1/J unknown male 00-00-0000
PH00282 B6D2F1/J unknown male 00-00-0000
PH00283 B6D2F1/J unknown male 00-00-0000
PH00284 B6D2F1/J unknown male 00-00-0000
PH00296 BXD42 unknown male 00-00-0000
PH00297 BXD42 unknown male 00-00-0000
PH00300 BXD02 unknown male 00-00-0000
PH00303 BXD06 unknown male 00-00-0000
PH00304 BXD06 unknown male 00-00-0000
PH00305 BXD06 unknown male 00-00-0000
PH00309 BXD11 unknown male 00-00-0000
PH00310 BXD11 unknown male 00-00-0000
PH00311 BXD11 unknown male 00-00-0000
PH00312 BXD39 unknown male 00-00-0000
PH00313 BXD39 unknown male 00-00-0000
PH00335 BXD42 unknown male 00-00-0000
PH00369 B6D2F1/J unknown male 00-00-0000
PH00370 BXD31 unknown male 00-00-0000
PH00380 BXD02 unknown male 00-00-0000
PH00381 BXD02 unknown male 00-00-0000
PH00382 BXD02 unknown male 00-00-0000
PH00439 BXD23 unknown male 00-00-0000
PH00445 B6D2F1/J unknown male 00-00-0000
PH00446 B6D2F1/J unknown male 00-00-0000
PH00447 B6D2F1/J unknown male 00-00-0000
PH00449 B6D2F1/J unknown male 00-00-0000
PH00451 BXD38 unknown male 00-00-0000
PH00457 BXD62 unknown male 00-00-0000
PH00460 BXD06 unknown male 00-00-0000
PH00461 BXD06 unknown male 00-00-0000
PH00462 BXD06 unknown male 00-00-0000
PH00463 D2B6F1/J unknown male 00-00-0000
PH00526 BXD36 unknown male 00-00-0000
PH00625 BXD08 unknown male 00-00-0000
PH00657 BXD31 unknown male 00-00-0000
PH00750 D2B6F1/J unknown male 00-00-0000
PH00752 D2B6F1/J unknown male 00-00-0000
PH00753 D2B6F1/J unknown male 00-00-0000
PH00754 D2B6F1/J unknown male 00-00-0000
PH00785 D2B6F1/J unknown male 00-00-0000
PH00786 D2B6F1/J unknown male 00-00-0000
PH00787 BXD42 unknown male 00-00-0000
PH00788 BXD42 unknown male 00-00-0000
PH00789 BXD42 unknown male 00-00-0000
PH00790 BXD33 unknown male 00-00-0000
PH00791 BXD33 unknown male 00-00-0000
PH00914 D2B6F1/J unknown male 00-00-0000
PH00915 D2B6F1/J unknown male 00-00-0000
PH00916 BXD39 unknown male 00-00-0000
PH00940 B6D2F1/J unknown male 00-00-0000
PH00942 B6D2F1/J unknown male 00-00-0000
PH00945 B6D2F1/J unknown male 00-00-0000
PH00949 BXD75 unknown male 00-00-0000
PH00952 BXD75 unknown male 00-00-0000
PH00996 BXD08 unknown male 00-00-0000
PH00998 BXD08 unknown male 00-00-0000
PH00999 BXD01 unknown male 00-00-0000
PH01001 BXD01 unknown male 00-00-0000
PH01012 BXD62 unknown male 00-00-0000
PH01013 BXD62 unknown male 00-00-0000
PH01014 BXD62 unknown male 00-00-0000
PH01031 BXD32 unknown male 00-00-0000
PH01032 BXD32 unknown male 00-00-0000
PH01047 BXD69 unknown male 00-00-0000
PH01048 BXD69 unknown male 00-00-0000
PH01049 BXD69 unknown male 00-00-0000
PH01050 BXD69 unknown male 00-00-0000
PH01051 BXD69 unknown male 00-00-0000
PH01078 BXD01 unknown male 00-00-0000
PH01079 BXD01 unknown male 00-00-0000
PH01080 BXD01 unknown male 00-00-0000
PH01082 BXD51 unknown male 00-00-0000
PH01083 BXD51 unknown male 00-00-0000
PH01084 BXD51 unknown male 00-00-0000
PH01085 BXD51 unknown male 00-00-0000
PH01086 BXD51 unknown male 00-00-0000
PH01087 BXD51 unknown male 00-00-0000
PH01089 BXD75 unknown male 00-00-0000
PH01091 BXD75 unknown male 00-00-0000
PH01092 BXD75 unknown male 00-00-0000
PH01094 BXD68 unknown male 00-00-0000
PH01095 BXD68 unknown male 00-00-0000
PH01096 BXD90 unknown male 00-00-0000
PH01097 BXD90 unknown male 00-00-0000
PH01127 BXD42 unknown male 00-00-0000
PH01128 BXD42 unknown male 00-00-0000
PH01129 BXD42 unknown male 00-00-0000
PH01131 BXD42 unknown male 00-00-0000
PH01132 BXD42 unknown male 00-00-0000
PH01133 BXD68 unknown male 00-00-0000
PH01210 BXD21 unknown male 00-00-0000
PH01211 BXD21 unknown male 00-00-0000
PH01213 BXD21 unknown male 00-00-0000
PH01214 BXD21 unknown male 00-00-0000
PH01229 BXD01 unknown male 00-00-0000
PH01231 BXD01 unknown male 00-00-0000
PH01232 BXD36 unknown male 00-00-0000
PH01236 BXD36 unknown male 00-00-0000
PH01238 BXD90 unknown male 00-00-0000
PH01239 BXD90 unknown male 00-00-0000
PH01241 BXD90 unknown male 00-00-0000
PH01245 BXD90 unknown male 00-00-0000
PH01246 BXD08 unknown male 00-00-0000
PH01247 BXD08 unknown male 00-00-0000
PH01248 BXD13 unknown male 00-00-0000
PH01249 BXD13 unknown male 00-00-0000
PH01251 BXD13 unknown male 00-00-0000
PH01252 BXD13 unknown male 00-00-0000
PH01253 BXD13 unknown male 00-00-0000
PH01257 BXD51 unknown male 00-00-0000
PH01258 BXD51 unknown male 00-00-0000
PH01259 BXD51 unknown male 00-00-0000
PH01260 BXD51 unknown male 00-00-0000
PH01262 BXD51 unknown male 00-00-0000
PH01263 BXD51 unknown male 00-00-0000
PH01357 BXD32 unknown male 00-00-0000
PH01358 BXD32 unknown male 00-00-0000
PH01407 BXD40 unknown male 00-00-0000
PH01408 BXD40 unknown male 00-00-0000
PH01409 BXD40 unknown male 00-00-0000
PH01410 BXD40 unknown male 00-00-0000
PH01411 BXD23 unknown male 00-00-0000
PH01415 BXD34 unknown male 00-00-0000
PH01416 BXD34 unknown male 00-00-0000
PH01427 BXD43 unknown male 00-00-0000
PH01428 BXD43 unknown male 00-00-0000
PH01429 BXD43 unknown male 00-00-0000
PH01430 BXD61 unknown male 00-00-0000
PH01435 BXD90 unknown male 00-00-0000
PH01436 BXD90 unknown male 00-00-0000
PH01437 BXD62 unknown male 00-00-0000
PH01439 BXD23 unknown male 00-00-0000
PH01440 BXD23 unknown male 00-00-0000
PH01441 BXD23 unknown male 00-00-0000
PH01444 BXD73 unknown male 00-00-0000
PH01445 BXD73 unknown male 00-00-0000
PH01474 BXD11 unknown male 00-00-0000
PH01475 BXD13 unknown male 00-00-0000
PH01476 BXD13 unknown male 00-00-0000
PH01482 BXD73 unknown male 00-00-0000
PH01486 BXD73 unknown male 00-00-0000
PH01589 BXD73 unknown male 00-00-0000
PH01596 BXD06 unknown male 00-00-0000
PH01597 BXD06 unknown male 00-00-0000
PH01598 BXD06 unknown male 00-00-0000
PH01888 BXD96 unknown male 00-00-0000
PH01908 BXD96 unknown male 00-00-0000
PH01916 BXD69 unknown male 00-00-0000
PH01917 BXD69 unknown male 00-00-0000
PH01918 BXD69 unknown male 00-00-0000
PH01919 BXD69 unknown male 00-00-0000
PH01920 BXD69 unknown male 00-00-0000
PH01973 BXD55 unknown male 00-00-0000
PH01975 BXD39 unknown male 00-00-0000
PH02031 BXD31 unknown male 00-00-0000
PH02032 BXD31 unknown male 00-00-0000
PH02035 BXD32 unknown male 00-00-0000
PH02063 BXD02 unknown male 00-00-0000
PH02065 BXD33 unknown male 00-00-0000
PH02066 BXD33 unknown male 00-00-0000
PH02068 BXD31 unknown male 00-00-0000
PH02069 BXD31 unknown male 00-00-0000
PH02070 BXD31 unknown male 00-00-0000
PH02080 BXD87 unknown male 00-00-0000
PH02081 BXD87 unknown male 00-00-0000
PH02083 BXD87 unknown male 00-00-0000
PH02084 BXD43 unknown male 00-00-0000
PH02085 BXD43 unknown male 00-00-0000
PH02086 BXD43 unknown male 00-00-0000
PH02087 BXD43 unknown male 00-00-0000
PH02088 BXD43 unknown male 00-00-0000
PH02089 BXD43 unknown male 00-00-0000
PH02090 BXD61 unknown male 00-00-0000
PH02091 BXD61 unknown male 00-00-0000
PH02092 BXD61 unknown male 00-00-0000
PH02093 BXD61 unknown male 00-00-0000
PH02094 BXD61 unknown male 00-00-0000
PH02096 BXD61 unknown male 00-00-0000
PH02097 BXD05 unknown male 00-00-0000
PH02098 BXD05 unknown male 00-00-0000
PH02174 BXD55 unknown male 00-00-0000
PH02176 BXD55 unknown male 00-00-0000
PH02177 BXD55 unknown male 00-00-0000
PH02178 BXD55 unknown male 00-00-0000
PH02179 BXD55 unknown male 00-00-0000
PH02180 BXD55 unknown male 00-00-0000
PH02182 BXD65 unknown male 00-00-0000
PH02183 BXD65 unknown male 00-00-0000
PH02184 BXD65 unknown male 00-00-0000
PH02359 BXD39 unknown male 00-00-0000
PH02360 BXD39 unknown male 00-00-0000
PH02361 BXD39 unknown male 00-00-0000
PH02442 BXD34 unknown male 00-00-0000
PH02444 BXD34 unknown male 00-00-0000
PH02445 BXD34 unknown male 00-00-0000
PH02446 BXD34 unknown male 00-00-0000
PH02448 BXD34 unknown male 00-00-0000
PH02449 BXD34 unknown male 00-00-0000
PH02450 BXD34 unknown male 00-00-0000
PH02451 BXD34 unknown male 00-00-0000
PH02452 BXD24 unknown male 00-00-0000
PH02453 BXD55 unknown male 00-00-0000
PH02455 BXD55 unknown male 00-00-0000
PH02456 BXD55 unknown male 00-00-0000
PH02458 BXD55 unknown male 00-00-0000
PH02460 BXD55 unknown male 00-00-0000
PH02461 BXD55 unknown male 00-00-0000
PH02462 BXD55 unknown male 00-00-0000
PH02464 BXD55 unknown male 00-00-0000
PH02466 BXD55 unknown male 00-00-0000
PH02467 BXD55 unknown male 00-00-0000
PH02489 BXD73 unknown male 00-00-0000
PH02491 BXD73 unknown male 00-00-0000
PH02492 BXD61 unknown male 00-00-0000
PH02493 BXD61 unknown male 00-00-0000
PH02494 BXD61 unknown male 00-00-0000
PH02497 BXD69 unknown male 00-00-0000
PH02498 BXD69 unknown male 00-00-0000
PH02500 BXD69 unknown male 00-00-0000
PH02519 BXD39 unknown male 00-00-0000
PH02520 BXD39 unknown male 00-00-0000
PH02521 BXD39 unknown male 00-00-0000
PH02522 BXD39 unknown male 00-00-0000
PH02524 BXD39 unknown male 00-00-0000
PH02526 BXD33 unknown male 00-00-0000
PH02529 BXD08 unknown male 00-00-0000
PH02550 BXD61 unknown male 00-00-0000
PH02583 BXD61 unknown male 00-00-0000
PH02584 BXD61 unknown male 00-00-0000
PH02585 BXD61 unknown male 00-00-0000
PH02586 BXD61 unknown male 00-00-0000
PH02587 BXD61 unknown male 00-00-0000
PH02592 BXD13 unknown male 00-00-0000
PH02593 BXD13 unknown male 00-00-0000
PH02594 BXD13 unknown male 00-00-0000
PH02596 BXD13 unknown male 00-00-0000
PH02597 BXD13 unknown male 00-00-0000
PH02729 BXD24 unknown male 00-00-0000
PH02733 BXD24 unknown male 00-00-0000
PH02734 BXD24 unknown male 00-00-0000
PH02735 BXD24 unknown male 00-00-0000
PH02736 BXD24 unknown male 00-00-0000
PH02738 BXD24 unknown male 00-00-0000
PH02739 BXD24 unknown male 00-00-0000
PH02781 BXD32 unknown male 00-00-0000
PH02782 BXD32 unknown male 00-00-0000
PH02783 BXD32 unknown male 00-00-0000
PH02784 BXD32 unknown male 00-00-0000
PH02785 BXD32 unknown male 00-00-0000
PH02832 BXD14 unknown male 00-00-0000
PH02834 BXD15 unknown male 00-00-0000
PH02835 BXD15 unknown male 00-00-0000
PH02839 BXD15 unknown male 00-00-0000
PH02840 BXD15 unknown male 00-00-0000
PH02841 BXD15 unknown male 00-00-0000
PH02842 BXD15 unknown male 00-00-0000
PH02851 BXD86 unknown male 00-00-0000
PH02852 BXD86 unknown male 00-00-0000
PH02853 BXD86 unknown male 00-00-0000
PH02854 BXD86 unknown male 00-00-0000
PH02855 BXD86 unknown male 00-00-0000
PH02865 BXD98 unknown male 00-00-0000
PH02866 BXD98 unknown male 00-00-0000
PH02872 BXD08 unknown male 00-00-0000
PH02873 BXD08 unknown male 00-00-0000
PH02874 BXD08 unknown male 00-00-0000
PH02886 BXD55 unknown male 00-00-0000
PH02888 BXD55 unknown male 00-00-0000
PH02890 BXD55 unknown male 00-00-0000
PH02892 BXD55 unknown male 00-00-0000
PH02927 BXD33 unknown male 00-00-0000
PH02929 BXD33 unknown male 00-00-0000
PH02936 BXD96 unknown male 00-00-0000
PH02937 BXD96 unknown male 00-00-0000
PH02940 BXD96 unknown male 00-00-0000
PH02941 BXD96 unknown male 00-00-0000
PH02955 BXD75 unknown male 00-00-0000
PH02956 BXD75 unknown male 00-00-0000
PH02960 BXD75 unknown male 00-00-0000
PH02961 BXD68 unknown male 00-00-0000
PH02969 BXD90 unknown male 00-00-0000
PH02970 BXD90 unknown male 00-00-0000
PH02973 BXD90 unknown male 00-00-0000
PH02986 BXD87 unknown male 00-00-0000
PH02987 BXD87 unknown male 00-00-0000
PH02988 BXD87 unknown male 00-00-0000
PH02989 BXD87 unknown male 00-00-0000
PH02990 BXD87 unknown male 00-00-0000
PH02993 BXD62 unknown male 00-00-0000
PH02996 BXD62 unknown male 00-00-0000
PH02997 BXD62 unknown male 00-00-0000
PH02998 BXD62 unknown male 00-00-0000
PH02999 BXD62 unknown male 00-00-0000
PH03000 BXD62 unknown male 00-00-0000
PH03001 BXD62 unknown male 00-00-0000
PH03002 BXD62 unknown male 00-00-0000
PH03004 BXD62 unknown male 00-00-0000
PH03005 BXD62 unknown male 00-00-0000
PH03006 BXD62 unknown male 00-00-0000
PH03013 BXD69 unknown male 00-00-0000
PH03015 BXD69 unknown male 00-00-0000
PH03118 BXD43 unknown male 00-00-0000
PH03119 BXD43 unknown male 00-00-0000
PH03122 BXD43 unknown male 00-00-0000
PH03125 BXD86 unknown male 00-00-0000
PH03126 BXD86 unknown male 00-00-0000
PH03127 BXD86 unknown male 00-00-0000
PH03128 BXD86 unknown male 00-00-0000
PH03129 BXD05 unknown male 00-00-0000
PH03130 BXD05 unknown male 00-00-0000
PH03131 BXD05 unknown male 00-00-0000
PH03132 BXD05 unknown male 00-00-0000
PH03133 BXD05 unknown male 00-00-0000
PH03134 BXD05 unknown male 00-00-0000
PH03135 BXD24 unknown male 00-00-0000
PH03136 BXD24 unknown male 00-00-0000
PH03138 BXD24 unknown male 00-00-0000
PH03140 BXD01 unknown male 00-00-0000
PH03141 BXD01 unknown male 00-00-0000
PH03142 BXD01 unknown male 00-00-0000
PH03143 BXD01 unknown male 00-00-0000
PH03151 BXD14 unknown male 00-00-0000
PH03152 BXD14 unknown male 00-00-0000
PH03153 BXD14 unknown male 00-00-0000
PH03155 BXD14 unknown male 00-00-0000
PH03156 BXD14 unknown male 00-00-0000
PH03158 BXD32 unknown male 00-00-0000
PH03159 BXD32 unknown male 00-00-0000
PH03160 BXD32 unknown male 00-00-0000
PH03161 BXD32 unknown male 00-00-0000
PH03162 BXD32 unknown male 00-00-0000
PH03163 BXD32 unknown male 00-00-0000
PH03164 BXD14 unknown male 00-00-0000
PH03166 BXD14 unknown male 00-00-0000
PH03187 BXD14 unknown male 00-00-0000
PH03188 BXD14 unknown male 00-00-0000
PH03190 BXD14 unknown male 00-00-0000
PH03193 BXD86 unknown male 00-00-0000
PH03194 BXD86 unknown male 00-00-0000
PH03197 BXD86 unknown male 00-00-0000
PH03199 BXD86 unknown male 00-00-0000
PH03200 BXD61 unknown male 00-00-0000
PH03201 BXD61 unknown male 00-00-0000
PH03202 BXD61 unknown male 00-00-0000
PH03204 BXD61 unknown male 00-00-0000
PH03205 BXD40 unknown male 00-00-0000
PH03207 BXD40 unknown male 00-00-0000
PH03208 BXD40 unknown male 00-00-0000
PH03209 BXD11 unknown male 00-00-0000
PH03211 BXD86 unknown male 00-00-0000
PH03212 BXD86 unknown male 00-00-0000
PH03213 BXD86 unknown male 00-00-0000
PH03214 BXD08 unknown male 00-00-0000
PH03236 BXD08 unknown male 00-00-0000
PH03237 BXD08 unknown male 00-00-0000
PH03238 BXD08 unknown male 00-00-0000
PH03239 BXD14 unknown male 00-00-0000
PH03240 BXD14 unknown male 00-00-0000
PH03242 BXD34 unknown male 00-00-0000
PH03243 BXD34 unknown male 00-00-0000
PH03244 BXD34 unknown male 00-00-0000
PH03246 BXD34 unknown male 00-00-0000
PH03247 BXD34 unknown male 00-00-0000
PH03251 BXD34 unknown male 00-00-0000
PH03253 BXD08 unknown male 00-00-0000
PH03254 BXD15 unknown male 00-00-0000
PH03255 BXD15 unknown male 00-00-0000
PH03256 BXD15 unknown male 00-00-0000
PH03257 BXD15 unknown male 00-00-0000
PH03258 BXD15 unknown male 00-00-0000
PH03259 BXD15 unknown male 00-00-0000
PH03260 BXD24 unknown male 00-00-0000
PH03261 BXD24 unknown male 00-00-0000
PH03262 BXD24 unknown male 00-00-0000
PH03263 BXD24 unknown male 00-00-0000
PH03264 BXD98 unknown male 00-00-0000
PH03265 BXD98 unknown male 00-00-0000
PH03266 BXD98 unknown male 00-00-0000